Effects of an exercise program on physiological variables and 6 Minute walk test in obesity

Authors

DOI:

https://doi.org/10.47197/retos.v72.114249

Keywords:

Exercise, functional capacity, obesity, physiological adaptation, six-minute walk test

Abstract

Introduction: Obesity represents a clinical and public health challenge that requires comprehensive, evidence-based strategies.

Objective: To describe changes in aerobic capacity and physiological variables in adults with grade II and III obesity after participating in a multidisciplinary program that included supervised exercise, nutritional support, and psychological counseling.

Methodology: Prospective longitudinal study based on the medical records of patients who completed 24 or 36 supervised exercise sessions (twice a week, 60 minutes). Aerobic capacity was assessed using the six-minute walk test (6MWT), and anthropometric, hemodynamic, and respiratory variables were recorded before and after the intervention.

Results: Sixty-two patients (83.9% women) were included, of whom 67.7% had at least one comorbidity. After the program, significant reductions in body weight and body mass index (p < 0.05) were observed, with moderate to large effect sizes. The 6MWT showed significant improvements in heart rate, respiratory rate, and systolic and diastolic blood pressure, while changes in oxygen saturation were minimal and clinically irrelevant. The distance walked increased by an average of 22 meters, accompanied by modest increases in estimated VO₂ and METs. However, most changes did not reach clinically relevant thresholds.

Conclusions: Completing a multidisciplinary program with supervised moderate-to-vigorous exercise improved some functional and physiological parameters in adults with severe obesity, although the magnitude of the benefits was limited, highlighting the need for longer and more intensive interventions.

Author Biographies

  • Alejandro Segura Ordoñez, Universidad Santiago de Cali
    1. Grupo de investigación Salud y Movimiento. Universidad Santiago de Cali. Cali, Colombia.
    2. Grupo de investigación Nutrición. Universidad del Valle. Cali, Colombia.
  • Sebastian Yara Muñoz, Universidad del Valle

    Grupo de investigación en Rehabilitación (GIRUV). Universidad del Valle. Cali, Colombia.

  • Nathali Carvajal, Universidad Santiago de Cali
    1. Grupo de investigación Salud y Movimiento. Universidad Santiago de Cali. Cali, Colombia.
  • David Alexander Lemos Martínez, Fundación Valle del Lili
    1. Centro de investigaciones clínicas. Fundación Valle del Lili. Cali, Colombia.
  • José Guillermo Ortega, Universidad Javeriana Cali
    1. Grupo de investigación de ciencias básicas y clínicas de la salud. Pontificia Universidad Javeriana Cali. Cali, Colombia.
  • Mildrey Mosquera, Universidad del Valle

    1 Grupo de Nutrición, Departamento de Ciencias Fisiológicas, Facultad de Salud, Universidad del Valle.

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15-09-2025

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Segura Ordoñez, A., Yara Muñoz, S., Carvajal, N., Lemos Martínez, D. A., Ortega, J. G., & Mosquera, M. (2025). Effects of an exercise program on physiological variables and 6 Minute walk test in obesity. Retos, 72, 425-435. https://doi.org/10.47197/retos.v72.114249